The effects of high-flow nasal oxygen applications on respiratory and hemodynamic parameters related to obesity in sedoanalgesia-assisted probe curettage procedures

Our study aims to investigate if hemodynamic, respiratory, and arterial blood gas analysis differs between patient groups who are obese and those that are not, and whether these differences change based on whether nasal or high-flow oxygen is used. Materials/Methods This study was conducted with an observational prospective design at Erzincan Mengücek Gazi Training and Research Hospital. The study included 120 ASA I–II patients who were scheduled for elective probe curettage surgery at the clinic for obstetrics and gynecology. Each of the two groups—those receiving high-flow nasal oxygen and those receiving oxygen through a nasal cannula—was further split into groups for obese and nonobese individuals. The patients' arterial blood gas, respiratory, and hemodynamic data were examined. Results In comparison to non-obese patient groups, obese patient groups had greater systolic, diastolic, and mean arterial pressures, respiratory rates, number of desaturations, number of airway interventions, pH, and HCO3 levels; conversely, they had lower SpO2, oxygen reserve index, and ROX index. When compared to the high-flow oxygen group, the nasal oxygen group had lower SpO2, oxygen reserve index, and ROX index, and higher respiratory rate, airway interventions, diastolic and mean arterial pressures. As opposed to Group 2, Group 1 had lower pH, pCO2, HCO3, respiratory rate, desaturation number, systolic, diastolic, and mean arterial pressures as well as lower levels of oxygen reserve index, Horowitz index, and SpO2. In comparison to Group 4, Group 3 had lower levels of pulse, systolic, diastolic, mean arterial pressures, respiratory rate, pH, pCO2, and HCO3 but higher levels of SpO2, ROX index, pO2, and Horowitz index. In comparison to Group 3, Group 1 had a lower pH and ROX index as well as a faster respiratory rate. Comparing Group 2 to Group 4, Group 2 had greater systolic, diastolic, and mean arterial pressures, respiratory rate, desaturation number, airway intervention, and pCO2 levels, but lower SpO2, pH, pO2, oxygen reserve index, Horowitz index, and ROX index. 3 Conclusion Many respiratory issues can arise from obesity, especially in patients undergoing sedation in an operating room setting. These issues can be attributed to limited lung capacity, compromised gas exchange, and a higher likelihood of adverse effects. The unfavorable consequences that can occur in these patients may not be sufficiently prevented by conventional low-flow nasal oxygen assistance. We investigated the effects of nasal oxygen and high-flow oxygen support on patients who were obese and those who were not. We came to the conclusion that employing high-flow oxygen support can help avoid the drawbacks and problems in arterial blood gas, respiratory, and hemodynamic findings brought on by obesity. Consequently, we think that high-flow oxygen assistance is preferable, particularly for procedures involving sedation in obese individuals.