Determination of some work and heavy metal (zinc, copper, magnesium, manganese, iron, lead and cadmium) levels in cytrotic liver patients

In this study, some trace and heavy metal (Cu, Zn, Fe, Cd, Pb, Mg and Mn) levels were investigated in cirrhotic liver patients. For this purpose, blood samples were obtained from 30 patients and 30 normal healthy individuals who were hospitalized with the diagnosis of liver cirrhosis in Batman Regional State Hospital. Samples of levels of serum Cu, Zn, Fe, Cd, Pb, Mg and Mn were measured by Atomic Absorption Spectroscopy (AAS) within the scope of the study, and statistical studies of the quantitative measurement results obtained for the cirrhosis group and healthy control group were performed. According to these results, the difference between the mean concentrations of the control group and the patient group was significant (p<0.05) for all elements (Cu, Zn, Fe, Cd, Pb, Mg and Mn). Again, when the results obtained are evaluated, the concentration of Cu, Zn, Fe, Mg and Mn should be in human body is lower in patients with cirrhosis than in healthy individuals. The concentrations of Cd and Pb which are harmful to human body and toxic effects were found to be higher than healthy individuals. As a result, it can be said that elements such as Cu, Zn, Fe, Cd, Pb, Mg and Mn affect the disease and play an important role in the etiopathogenesis of liver cirrhosis.