The effect of clinoptilolite (zeolite) administration on abomasal emptyi̇ng rate in calves

Objective: With the planned research, it was aimed to determine the effect of clinoptilolite (zeolite), which is known to have preventive and therapeutic effects against diarrhea in calves, on the abomazal discharge rate. Material and Methods: In this context, the Holstein breed neonatal calves in both sexes were diveded in to two equal groups (n=7). Zeolite (1 g/kg) and acidaminophen (50 mg/kg) were added to the milk to the calves in the zeolite group, and only acetaminophen was added to the control group. Blood samples were taken at 0. minutes before the application and at 30., 60., 90., 120., 180., 240., 300. minutes after the application. Results: Considering the changes in plasma acetaminophen concentrations in time-dependent plasma levels, it was determined that there were no significant changes at the end of the study between the zeolite and control group calves. On the other hand, when the time to reach the maximum concentration of both groups was examined, it was observed that the Tmax time was significantly lower than the calves in the control group, and the acetaminophen absorption was higher in the calves treated with zeolite. Conclusion: Abomazal ejaculation time was shorter in zeolite-treated calves compared to control group calves. It was determined that zeolite, which has a prophylactic and therapeutic effect against diarrhea, does not have a negative effect on abomazal emptying and is a safe agent to use.