Evaluation of serum ferritin level, i̇nsulin resistance and nutritional status of adult subjects WHO have referred to A private medical center policlinic

This study aims to find out risk factors of insulin resistance that related to nutrition, determine corelation between, serum ferritin, insulin resistance and nutritional status. The study has been carried out on 109 adult individuals in total, composed of 92 (%84.4) females and 17 (%15.6) males, that applied to city of Ankara Private New Middle East Surgical Medical Center, internal medicine policlinic between the dates of November 2015-February 2016. Individuals' demographic properties, phisical activity states and some eating habits are questionned with surveys. Some biochemical parameters, antrophometric measurements and three days nutrition consumptions were recorded. Individuals that applied to this study seperated four quartiels according to their serum ferritin level; if serum ferritin level ≤18.1 ng/mL, quartile1 (Q1), if serum ferritin level between 18.2-31.1 ng/mL, quartile2 (Q2), if serum ferritin is between 31.2-73.35 ng/mL, quartile3 (Q3) and if serum ferritin ≥73.36 ng/mL quartile4 (Q4). Furthermore, individuals that Homeosthasis model assesment-Insulin resistance (HOMA-IR) level were belove 2.7 were formed group that has no insulin resistence and individuals that HOMA-IR level were above 2.7 were formed group that have insulin resistence. The average age of male individuals was 32.4±10.44 years and 37.0±10.65years for female individuals. According to body mass index grouping, following were defined that fat female individuals (BMI ≥30.0 kg/m2) %69.2 percentage were in Q1, %59.3 were in Q2, %33.4 were in Q3 and %86.7 were in Q4 and this difference were meaningful statistically. Individuals' that are in Q1 and Q4 waist circumference measurement (100.1±9.58 cm, 103.8±8.47 cm) are bigger than individuals that are in Q2 and Q3 (95.6±10.8 cm, 94.2±13.4 cm). Accoding to quartiles, when looked HOMA-IR levels, HOMA-IR levels of Q4 individuals (4.1±2.66) were higher than other quartiles (p<0.05). Serum fasting insulin and serum iron levels of Q4 were meaningfully higher than other qroups; serum HDL cholesterole is smaller than other quartiles (p<0.05). Serum ferritin level, individuals that have insulin resistance (71.1±70.28 ng/mL) were found meaningfully higher than individuals that does not have insulin resistence (42.9±37.55 ng/mL). İron level that intake daily diet, individuals that have insulin resistance (15.9±4.47 mg) were meaningfully higher than individuals that does not have insulin resistance (13.8±3.07 mg) (p<0.05). According to ferritin quartiles, iron level of daily diets were found that at Q1 15.0±3.60 mg, at Q2 14.6±3.25 mg, at Q3 16.1±3.25 mg and at Q4 14.8±2.61mg and found that there is not statistical difference between quartiles (p>0.05). Daily energy of carbonhydrates at Q1 and Q4 were found higher than Q2 and Q3 (p<0.05). Serum ferritin level insulin resistance and serum iron are correlated positively. As a result; following result is found that serum iron, iron level intaken with diet and serum ferritin levels are risk factor of insulin resistance, avoiding of these risk factors, individual based nutrition order created and lifestile changes should be recommended.