Infections in intensive care of newborn, antibiotic use and bacteric resistance against these antibiotics

In recent years, due to advances in neonatology, premature babies with low birth weight have been living and these babies have been followed up in neonatal intensive care units for a long time. However, long-term hospitalization brings with it various complications. The most important of these complications are hospital infections. Especially infants in the intensive care unit carry more risk factors for these hospital infections than other infants. The most important of these risk factors are low birth weight, premature birth, mechanical ventilator and catheter applications. Patients hospitalized in the neonatal intensive care units of the Private Lokman Hekim Hospital in Van between 2015-2018 were retrospectively reviewed from the hospital's data processing database and a total of 310 patients were included in the study. Patients' demographic characteristics, catheter status, mechanical ventilation status, duration of infection, hospitalization periods, whether to undergo surgical treatment, the most common microorganisms, antibiogram results of patients, antibiotics used in infants by years and the type of infection and antibiotic resistance rates were viewed. In our study, Gr + Staphylococcus epidermidis (57%) was the most common pathogen in blood culture. Gr - Escherichia coli (11%) and Klebsiella (10%) followed. In urine culture, the most common pathogens were E.coli (58%), Staphylococcus epidermidis (13%) and Enterobacter (13%), respectively. It is seen that gram negative bacteria do not develop resistance to Levofloxacin, Moxifloxacin, Imipenem and Vancomycin antibiotics and it is seen that gram positive bacteria generally show lower resistance than gram negative bacteria. The results of our study show that infants hospitalized in neonatal intensive care units consist mostly of preterm-SGA patients, the duration of hospitalization is long, the catheter usage and infection rate is quite high. Key words: Antibiotic, resistance, infection, premature, newborn.