Evaluation of patiens who wereoperated for malin-gnant adnexal mass and who applied to The Department of Obstetrics and Gynecology of Dicle Universİty between 2011-2020

Objective: In this study, considering all the known facts about ovarian cancer; The aim of this study is to retrospectively examine the factors related to the etiopathogenesis, diagnosis and prognosis of ovarian cancer, to determine the population at risk, and to try to catch cancer before it progresses or at an early stage by controlling it more frequently and early. Material and Methods: A total of 99 patients who were operated for adnexal mass in Dicle University Faculty of Medicine, Department of Obstetrics and Gynecology between 1 January 2011 and 31 December 2020 and whose final pathology resulted as malignant were included in our study. Patients with borderline results were not included in our study. Of these 99 patients, age at 0, gravity-parity, menopausal status, presence of additional disease, symptoms, CA-125 level, tumor burden, tumor diameter and structure, presence of ascites, presence of implant, lymph node involvement, frozen pathology result, tumor type, stage, complications were investigated. Results: In this study, the mean age at diagnosis was 51.04 years. It was observed that 55.6% of the patients were postmenopausal. The most common tumor type was identified as epithelial tumors. It has been determined that the patients are mostly in the advanced stage. It has been observed that the universe progresses as the CA-125 level rises. When the relationship between the stage and the presence of lymph node and ascites fluid was examined, it was observed that lymph node involvement and presence of ascitic fluid increased in advanced stages. It has been demonstrated that CA-125 is higher in patients with residual tumors. CA-125 level was found to be higher in patients with lymph node involvement than in patients without lymph node involvement. It was observed that the CA-125 level was higher in patients with ascites compared to those without. CA-125 was found to be higher in patients with bilateral tumors than in patients with unilateral tumors. It has been observed that the level of CA-125 in epithelial tumors is higher than in other tumor types. Conclusion: Our study revealed that ovarian cancer is mostly detected in advanced age, postmenopausal women and often in advanced stages. CA-125, which is the most commonly used tumor marker, was found to be associated with stage, residual tumor, lymph node involvement, presence of ascites fluid, bilaterality of the tumor, and tumor type. In addition, lymph node involvement and ascites fluid, which may be related to the stages, were also examined and it was determined that as the stage increased, lymph node involvement and the presence of ascites fluid showed parallelism.