To evalute the macular thicknesses in amblyopia measured by using optical coherence tomography

Purpose: To measure and compare macular thicknesses(MT) in patients that have amblyopia and unamblyopia eyes with optical coherence tomography (OCT) and to define OCT as a early diagnosis tool. Material-Method: 27 patients having amblyopia associated strabismus classified as grup 1, 18 patients having amblyopia associated anisometropia classified as grup 2 and 45 healthy volunteers classified as group 3 were enrolled into the study. All participants were underwent into the full ophtalmological examination and were measured MT by OCT. Results: There was a statistical significance between control group and group 1. (p=0,01)But there was not statistical significance between areas as we divided the macular thicknesses four quadrants. (supeiror macular-temporal macular-inferior macular-nasal macular). if we compare group 2 and control group there was statistical significance in temporal quadrants. (p=0,041). And there was not significantly difference between the other quadrants and central macula thicknesses. (p<0,05). There was a significantly difference between group 1 and group 2 in central macular area. (p=0,038). Other areas(supeiror macular-temporal macular-inferior macular-nasal macular) there was not statistical significance between group 1 and group 2. (p<0,05). Conclusion: Changes in macular thicknesses in strabismic amblyopia measured by OCT shows that structurel changes can develop in amblyopia. OCT gives hope as early diagnosis tool with the non-invasive feature in vivo. Keywords: Amblyopia, macular thickness, optical coherence tomography