Analysis of 217 cases amni̇ocentesi̇s

The main purpose in prenatal diagnose is to have information about fetus health and to make a decision about the future of fetus as soon as possible. Prenatal diagnose is divided in two groups as invasive procedures and non-invasive scanning . Non invasive tests are still being used in screening and for a definitive diagnosis, diagnosis should be confirmed by invasive procedures. Therefore invasive diagnosis still keeps it's importance in prenetal diagnosis. Despite increasing rate of coryonic villus sampling(CVS), genetic amniocentesis (AS) is still a common performed as a prenetal diagnosis procedure. Although AS could be performed in each trimester of pregnancy, genetic AS commonly performed between 15-20th weeks of gestation. This study was conducted between September 2011 and July 2013, and 217 patients included at the study. The patients who have had following indications underwent AS for a definitive diagnosis; pathological finding at family history and ultrasonography; high risk for double, triple and quadraple tests; advanced maternal age and maternal anxiety. High risk in triple test was the leading indication for AS followed by combine indications and pathological USG finding. The mean maternal age was 32.37±6.20 and mean gestation age was 17.58±1.80. AS was succesfully performed in each patient with one single try. The rate of chromosomal abnormality was found to be 8% in patients performed AS.No fetal loss occured due to AS. In case of performing AS with experts and high experienced doctors and if there is an optimum transport and culture conditions, it is an procedure with high reliability and accurancy. It's an important procedure for diagnosis with less complications seen due to the procedure.As a result, for definitive diagnosis of fetal chromosomal abnormalitiesi AS is still the most common used invasive method in prenatal diagnosis. Key words: prenatal diagnose,amniocentesis,chromosomal abnormality, indications, risks