Investigation of mycoplasma DNA structure in prostate tissues of patients who have benign prostate hyperplasia and prostate cancer diagnosis

In our study, to investigate mycoplasma DNA in benign and malignant prostate tissues of patients with a diagnosis of cancer and prostate tissues of patients with diagnosis of benign prostate hyperplasia were aimed. In this study tissue preparations of 31 patients with a diagnosis of benign prostate hyperplasia and 31 patients with prostate cancer diagnosis have been used and three study groups were composed. Group 1 was composed of tissues containing cancer of patients with prostate cancer diagnosis, group 2 included benign tissues of patients with prostate cancer diagnosis, and finally group 3 was composed of tissues of patients with a diagnosis of benign prostate hyperplasia (control group). Thirty-one preparations have been studied in each group. Mycoplasma DNA was investigated in preparations with PCR technique.Mycoplasma DNA was determined in 11 preparation of 31 patients in group 1 and 4 preparations of 31 patients in group 2. No mycoplasma DNA was determined in tissues of 31 patients in group 3.In conclusion, our data suggest that mycoplasma infections could be play a role in the etiology of prostate cancer. Further experimental and clinical studies are needed for development of a tool for early diagnosis and treatment of prostate cancer.