Evaluation of the role of preptin with vitamin D and parathyroid hormone in patients with renal failure

In our investigation, preptin levels were estimated in patients with complications of chronic renal disease, along with some biochemical indicators as vitamin D, calcium, blood urea, serum creatinine, and parathyroid hormone. The study included 40 healthy individuals as the control group and 60 patients with chronic renal disease, both of whom shared the same demographic characteristics. vitamin D levels are low on average compared to the control group, and they are significantly higher (P 0.002) in people with chronic renal disease. the mean of parathyroid hormone is above high compared with a control group and significant (P < 0.006) with chronic kidney disease, the mean of urea is high compared with a control group and it is significant (P < 0.004) with chronic kidney disease and creatinine mean is high compared with a control group and significant (P < 0.003) with chronic kidney disease, the mean of preptin was above the normal reference compared with a control group and it is significant (P < 0.007) with chronic kidney disease. Patients with chronic renal failure made up the experimental group in our study, which produced these results. Serum preptin concentrations correlated with blood urea r = 0.505, creatinine, r = 0.503, vitamin D r = - 0.452, and parathyroid hormone r = 0.322.