Comparison of corneal biomechanical properties in glaucoma patients using ocular response analyzer

Purpose: To evaluate corneal biomechanical properties in glaucoma patients (primary open angle glaucoma, normal tension glaucoma, pseudoexfoliation glaucoma) using the Ocular Response Analyzer. Methods: 114 primary open angle glaucoma, normal tension glaucoma and pseudoexfoliation glaucoma patients and 45 healthy volunteers (control group), total of 159 individuals were included in the study. Right eyes of 159 individuals were included in the study. Corneal compensated intraocular pressure, Goldmann correlated intraocular pressure, corneal hysteresis and corneal resistance factor were measured by Ocular Response Analyzer device. Results: The mean ages were 64.84, 66.86, 68.40 and 67.93 in primary open angle glaucoma, normal tension glaucoma, pseudoexfoliation glaucoma and control groups, respectively (p=0.272). Corneal compensated intraocular pressure values in primary open angle glaucoma and pseudoexfoliation glaucoma were statistically significantly higher than controls (p values 0.030 and 0.005, respectively). Corneal hysteresis values in open angle glaucoma and pseudoexfoliation glaucoma were statistically significantly lower than controls (p<0.001). Corneal hysteresis value in pseudoexfoliation glaucoma was statistically significantly lower than normal tension glaucoma (p=0.031). Corneal resistance factor value in pseudoexfoliation glaucoma was statistically significantly lower than controls (p=0.001). There were not statistically significant difference among Goldmann correlated intraocular pressure values (p=0.477). Conclusion: Corneal hysteresis decrease in primary open angle glaucoma, normal tension glaucoma and pseudoexfoliation glaucoma give rise to thought corneal biomechanical importance in glaucoma patients diagnose and follow-up. Key words: Glaucoma, Ocular Response Analyzer, corneal biomechanical properties.