Probiotic material application to chronic periodontitis patients after full mouth disinfection

The purpose of this study was to investigate the effects of orally administered tablets containing Lactobacillus reuteri DSM17938 ve Lactobacillus reuteri ATCC PTA5289 after full mouth disinfection (FMD) on periodontal health of patients with chronic periodontitis.60 systemically healthy patients with chronic periodontitis were included in the study. The patients were divided randomly into four groups. All patients' treatment was initiated after initial clinical measurements (pocket depth, attachment loss, gingival recession, plaque index, gingival index, bleeding on probing, mobility and furcation). Initial periodontal treatment was performed according to full mouth disinfection and quadrant approaches. Patients were divided as quadrant patients (15 patients-1st group) and full mouth disinfection group. FMD group was further divided into three groups: twelve week of placebo tablets (15 patients-2nd group), probiotic tablets for six weeks and six weeks placebo tablets (15 patients- 3rd group) and twelve weeks of probiotic tablets (15 patients-4th group). The clinical measurements were repeated in 3 week intervals. At the end of 12 weeks, the clinical data was statistically analyzed.The results of this study showed that all treatment groups provided statistically significant improvement on periodontal health while there were no differences between groups.Key Words: Probiotic Bacteria, Full Mouth Disinfection, Periodontal Treatment