Stomach cancer diagnosis of demographic data andclinical features in patients with retrospective study

Purpose: In this study; The demographic data and clinical features of patients with gastric cancer were retrospectively evaluated. Material and Method: In this study; 230 patients who were followed up with the diagnosis of gastric cancer in the Medical Oncology Department of İnönü University between 01.01.2010 and 10.10.2017 were examined. Patients with lymphoma, GİST and NET were excluded from the study. The remaining 201 patients were included in the study. 201 patients included in the study age, Eastern Cooperative Oncology Group (ECOG), presence of weight loss, primary site, histological type, tumor stage, patient's complaint, smoking, symptom duration, diagnostic method, surgery, surgical method, presence of metastasis, location of metastasis, first looked LDH and thrombocyte values, treatment methods and survival data were evaluated. Results and Conclusion: As a result of our study, male patients were found to be statistically significantly higher than female patients. There was a significant relationship between patient age and mean overall survival (p=0.014). The relationship between weight loss and advanced stage was statistically analyzed and a significant difference was found (p=0.005). There was also a significant difference between weight loss and mean overall survival (p <0.001). There was a significant difference between ECOG and mean overall survival (p=0.008). There was a significant difference between LDH value and mean overall survival (p <0.001). In our study, it was seen that overall survival decreased in advanced stage (p<0.001). Significant correlation was found between the primary site of tumor and mean overall survival (p=0.007). There was a significant relationship between the average survival rate and the patients with and without chemotherapy (p=0.003). The relationship between overall survival and adjuvant chemotherapy and palliative chemotherapy was investigated. A statistically significant relationship was found (p<0.001). Significant relationship was found between the type of chemotherapy and mean overall survival (p<0.035). There was a significant difference between surgery and mean overall survival (p<0.001). There was a significant difference between radiation therapy and mean overall survival (p<0.001). The independent variables which had significant effect on mean overall survival were investigaed using the multivariate Cox- Regression model. According to the results of the study, it was determined that the presence of surgery, LDH, weight loss and metastasis were independent prognostic factors. (p=0.005, p=0.048, p=0.014, p=0.005). Keywords: Gastric cancer, demographic data, overall survival Keywords: Gastric cancer, demographic data, overall survival