Study the effect of medicatins used for COVID patients on liver function in Iraqi people

The aim of this study is to compare the liver functions of patients recovering from Covid-19 to those of a healthy control group. Additionally to discover the relationships between the recovered group's liver functions and the medications they were taking, For the safety of the liver from damage. The study comprised 69 persons recovering from Covid-19, with an age range of (26-66) years, and their liver functions were compared to a group of 67 healthy adults with ages ranging of (19-62) years. The Pearson correlation was used to evaluate the relationship between the parameters and the medications (Ceftriaxone, Azithromycin, Levofloxacin, and Remdesivir) that were taken by the persons in the group recovering from Covid-19, The results showed that there were significant differences in the levels of enzymes ALT, AST, ALP, LDH, and albumin between the two study groups (p<0.001), while the results did not show any significant differences in total protein concentration between the two groups (p>0.05). The ALT concentration had a significant p<0.001 correlation with ceftriaxone R=0.443 and remdisivir R=0.441 in the group of recovered patients, while the AST enzyme had a significant correlation p<0.001 with ceftriaxone R=0.529, remdesivir R=0.455, and Azithromycin R=0.366. While LDH had a high correlation with azithromycin (ρ=0.566), ceftriaxone (ρ =0.517), and remdesivir (ρ =0.346).