Study IL 174C/G and IL10 1082T/G polymorphism in patients with COVID 19

This study aims to determine whether COVID19 infection is associated with variations in the IL-6 and IL-10 genes. In the study, samples were obtained from 20 healthy individuals as a control group and 90 individuals (male and female) with COVID-19 infection. IL-6 levels are significantly higher in COVID-19 infected patients than in healthy individuals. However, the data showed that the level of IL-10 in infected patients was significantly higher than in healthy ones. The serum vitamin D3 levels of infected patients were significantly lower than those of healthy controls. However, the results showed that infected patients had significantly higher vitamin B12 levels than healthy people. The data suggested that IL6 cytokines should be considered as a crucial factor in achieving the therapeutic response in people infected with COVID-19. The results showed a strong correlation between the frequency of the SNP gene and the severity of COVID-19 cases. Overall, the study's findings confirm that the increase in IL-10 and the decrease in lymphocytes are reliable indicators of COVID-19