Investigation of hypertension with ambulatory blood pressure monitoring in children with hydronephrosis caused by unilateral partial ureteropelvic junction obstuction

Objective: To investigate the tendency to hypertension in children with hydronephrosis caused by unilateral partial ureteropelvic junction obstuction and to examine the effects of isolated ureteropelvic junction obstruction on blood pressure.Research Design and Methods: The study was performed in Çukurova University Faculty of Medicine Pediatric Nephrology Department between 2009 and 2012. Patient group consisted of 19 children with unilateral partial ureteropelvic junction obstuction. Children were with normal renal function, had not been operated and had no additional renal pathology and systemic disease. Control group consisted of 19 healthy children who had no any known disease. Renal pelvis anteroposterior diameters were measured with ultrasonography. Clinic blood pressure measurements and 24 hour ambulatory blood pressure monitoring were performed to all children. Z scores were calculated with LMS method. Blood pressure loads and nocturnal dipping were examined. Statistical analyses was done with data obtained.Results: Z scores for night diastolic blood pressure (0,553 ? 0,833 in patient group, 0,132 ? 0,638 in control group) and night mean arterial pressure (0,804 ? 0,753 in patient group, 0,389 ? 0,688 in control group) were higher in patient group. Number of cases whose blood pressure loads for ?90th and ?95th percentiles exceed %30 and % 40 were higher statistically in patient group (9 cases ?% 30, 6 cases ?% 40 for loads ?90th percentile and 8 cases ?% 30, 4 cases ?% 40 for loads ?95th percentile in patient group. 3 cases ?% 30, 1 cases ?% 40 for loads ?90th percentile and 2 cases ?% 30, no cases ?% 40 for loads ?95th percentile in control group). İn patient group, the percentage of non-dipper cases was higher than the expected values in normal children.Conclusion: There was a tendency to hypertension in children with hydronephrosis caused by unilateral partial ureteropelvic junction obstuction. Although the patients were suitable for conservative management with normal renal function, their blood pressures were higher than the control group. The long term physiopathologic consequences should be evaluated in these patients who are preferably managed conservatively