The Retrospective analysis of patients with ARDS in The Intensive Care Unit

ABSTRACT Objective: ARDS is a serious restrictive syndrome, which leads to significant morbidity and mortality in intensive care. In studies, age, acute lung injury, chronic comorbid diseases, acute organ failure, severe sepsis / shock association, arterial blood gas values, GCS, SOFA, APACHE II, parameters such as LIS score was associated with prognosis and survival of the lung injury. In this study, we aimed to share the factors thought to be effective on mortality, in patients with ARDS in reanimation ICU. Materials and Methods:In this study, we aimed to compare of general characteristics, effects of etiologic and prognostic factors (mechanical ventilation applications, laboratory values, rates of mortality and multiorgan dysfunction, APACHE II, LIS, GCS, SOFA score, arterial blood gas values, PaO2/FiO2 ratio values) of patients with ARDS who diagnosed at Dicle University Clinic of Anesthesiology Intensive Care Unit between January 2009 and January 2013 on mortality and compare of patients who died and survived. Results: 61 patients with ARDS in our study male and 39 were female. When etiological factors of patients with ARDS investigated, 37 patients with pneumonia, 14 patients with trauma ( inside the vehicle and outside the vehicle and other accidents) , 19 patients with sepsis, 9 patients with pulmonary contusion, 6 patients with extrapulmonary infection, 5 patients with intoxication, 4 patients with multiple blood transfusions, 4 patients with Firearms weapon injuries, 2 patients with acute pancreatitis were found in. 44 of patients died. The mean age of the patients who died was significantly higher. APACHE II, SOFA, LIS scores were significantly higher in patients who died, GCS were significantly lower . PO2/FİO2 and PCO2 of blood gas values were significant. Duration of mechanical ventilation and length of stay in intensive care unit were significantly higher in patients who died. Organ failure and mortality was significantly higher in the presence of septic shock. Respiratory failure in patients with cardiac disease and diabetes mortality in patients with renal failure were significantly higher than the other comorbid conditions. Conclusion: ARDS is a common cause of significant morbidity and mortality in intensive care units. Early diagnosis and intensive care support, lung-protective mechanical ventilation and permissive hypercapnia strategy improve survival. In ARDS patients, age, chronic comorbid diseases, acute organ failure, association of severe sepsis / septic shock increases the mortality rate . Decreases of PaO2/FiO2 rate during diagnosis, in support of the prognostic significance of seriousness and severity of acute lung injury, increase mortality rates.