Investigation of pathology of rainbow trout (Oncorhynchus mykiss walbaum, 1792) infected with Aeromonas hydrophila

A total of eighty rainbow trout were used in this study. Three experimental and one control groups were made fkem those- Sates. Experimental groups were mfesfced with. Aeromomm hydrophila by smearing on the gills, intraperitoneal and intramuscularly injections of bacterium. Hyperemia and hemorrhage in the gills, parancfaima degeneration, neeroser descpanatios m epitlse&ifn. of Bowmanc capsule ia tfe. kktoeySr fayperesiig,. feöy degeneration, necrose and activation of kuppfer cells in the liver, edema.* hyperemia in dermis, congestion, îeucocyîic infiltration in collagen bundles of dermis and skeletal muscles- were observed, in. all experimental- groups. No histopathologic change, was. seen. in. gasteoâMesti»! ©tg»s.. of the: experisieiaal: groups: Tmmunohistoehemieal observation of gut hormons showed that no difference in between control and experimental groups. Glucagon immunoreactivity was seen in pancreas and small intestine. Insulin immunoreactivity was only localized ia pancreas. SafestfflsP imsmmmg&££İN'ûy wm seen w. the pyloric regioa of stesffi^eh m& $mâ\ irtestiaeLGastrin immuooreactivity was detected only localized in pyloric stomach. Gaibindin immuttoreadivity was not seen any organs examined. In electron microscopic investigation; large lipid droplets, degeneration in the endoplasmic reticulum, membraneous bodies and light staining area were had not have any organels were seen in the hepatasit of liver. Separation, of myofibrils*., lost of myofibrils saier the sar eoieffiffls were- sees is the skeletal muscles. A, I and Z fcaniles were sot seea clearly in the skeletal muscles. Large inclusions and some membraneous bodies and large structures as vacuols near the basal parts of cells were seen in the kidney. Key Wonfei Rainbow trout {Oncarhynchus mykiss},. Aerommms hydrophilcLr MsEopa&oksgy,. inmiiiKMstoefciBistry^ eteetroa microscopy.