The examination of the morphological changes in blood cells by extra corporeal circulation with peripherial blood smear under light microscope

The study was started after the approval of the ethics committee of the centenary Dursun Odabaşı Medical Center, dated 13/02/2019 and decision No: 07 (see Appendix 1). The volunteer informed consent form was signed for each patient. In this study, it was planned to examine the morphological changes of blood cells by extra corporeal circulation with peripherial blood smear under light microscope. This research was conducted on 33 patients of different ages who had cardiopulmoner bypass surgery. Those patients had been diagnosed on Dursun Odabası Medical Center of the University of Van Yuzuncu Yıl and they were been under control of the Cardiovasculer Surgery Depertmant. Patients that were diagnosed with coronary artery disease, coronary artery occlusion and damage heart valve replacement, aort disection and who were in need of surgical operation were also included in this study. The patients who had chronic kidney failure pregnancy, hematologic blood disease and who had the risk of hemotologic reaction has been excluded. The bloods of the patients who were decided to be taken into the cardiopulmoner bypass operation has been used for Peripherial Blood Smear. These blood samples were taken three times. One is just after being hospitalized, the second time was in the first hour after been applied the Extracororeal Circulation in tha intensiv care and the third time was on the planned discharce day. The healing process of the whole blood cells was observed. The effects of the operation duration the cross clamp period, the amaount of erythrocyte suspension and fresh frozen plasma, the type of the condition, the hemofiltration and the value of ejection on the formed elements of blood were determined. The values of the Peripherial Blood Smear were evaluated wing light microcope a Hb, Hct and Wbc values were compaired with hemogram. The values were analysed with regards to the World Healt Organisation's criteria. Staticstically significant differences were observed. The results were discussed on in accordance with the findings in the literature. Keywords: Extra Corporeal Circulation, Open Heart Surgery, Peripherial Blood Smear, Hemogram