In vitro bioactivities of some natural macrofungi in Hatay province

In this thesis, Pleurotus ostreatus (Jacq. ex Fr.) P. Kumm., Agaricus arvensis Schaeff., Suillus luteus (L.) Roussel, Cantharellus cibarius Fr., Coprinus comatus (O. F. Müll.) Pers., Fomes fomentarius (L.) Fr., Trametes gibbosa (Pers.) Fr., Laetiporus sulphureus (Bull.) Murrill, Lycoperdon molle Pers., Cerrena unicolor (Bull.) Murrill mushrooms collected from Hatay province and phenolic contents, element contents, total antioxidant levels (TOS), total oxidant levels (TOS), oxidative stress indices (OSI) and antimicrobial activities of macrofungus were determined. TAS, TOS and OSI values of fungi were determined with using Rel Assay kits. The highest TAS value was observed in Coprinus comatus (5.225±0.086). In addition, when TOS values were examined, it was determined that the highest TOS value was in Cerrena unicolor (20.577±0.270). In addition, when the OSI values were examined, it was determined that the highest OSI value was in Cerrena unicolor (2.151±0.085). The concentrations of ethanol extracts obtained from mushroom samples against growth inhibition against standard microorganisms were determined by agar dilution method. It was observed that the mushroom extracts used in our study were effective against microorganisms at different concentrations. In addition, the levels of some elements (Cr, Cu, Mn, Fe, Ni, Cd, Pb, Zn) in the mushroom samples were determined. In our study, it was observed that the element levels in the fungi were generally within the range of the literature. In order to determine their phenolic content, mushroom extracts were analyzed by Caponio et al. (1999) was studied by modifying the method using SHIMADZU system HPLC device and DAD detector. According to the data obtained as a result of this study, acetohydroxamic acid, luteolin, catechin, vanilic acid, syringic acid, resveratrol, fumaric acid, gallic acid, caffeic acid, hydoxycinamic acid, hydroxybenzoic acid, salicylic acid, myricetin, ellagic acid, quercetin, butein and naringenin were found.