Comparison of propofol and ketafol sedation in patients with interscalene and suprascular nerve block and shoulder surgery

Introduction and Purpose: We compared the effects of interscalene and suprascapular block, which are frequently used in shoulder surgery, for the purpose of sedation in anesthesia, the effects of propofol and ketofol on intraoperative and postoperative hemodynamics, respiratory parameters and sedation efficacy, and postoperative recovery and recovery room to discharge time. We aimed to achieve an effective sedation with stable hemodynamics, resulting in rapid recovery with early onset. Material Method: The study was carried out prospectively in a double-blind randomized study on ASA I and II patients aged 18-65, 21 patients in each group, and a total of 42 shoulder surgeries planned. Anesthesia was provided to the patients in the block room by performing interscalene and suprascapular nerve block with USG. Group 1 (Propofol) patient group, 1 mg/kg propofol IV was administered in 30-45 seconds. In Group 2 (Ketofol) patient group, a mixture of ketamine-propofol was prepared in a 1:1 ratio, 10mg injector with 5mg propofol and 5mg/ml ketamine. 1mg / kg ketofol IV was administered in 30-45 seconds. Processing was started in both groups when RSS was 3. Systolic blood pressure, diastolic blood pressure, mean blood pressure, pulse, O2 saturation, RSS, Face Scale, and exit value were recorded at 5 min intervals from the arrival of the monitorized patients taken to the operating table. The patients, whose surgery was completed, were taken to the post-op recovery room, and hemodynamic monitorization was performed. It was recorded whether there were any complaints of systolic blood pressure, diastolic blood pressure, mean blood pressure, pulse, saturation, RSS, Face Scale, Modified Aldrete Score, nausea, vomiting every 5 minutes from its arrival. The patients with an Aldrete score of 9 were terminated and sent to the service. Conclusion: When we compare ketofol and propofol, which we applied for sedation purposes, we found ketofol more effective when we looked at its effect on both depth and quality of sedation in terms of hemodynamics and complications, despite the rapid onset and rapid recovery of sedation with propofol. In post-op recovery, propofol is more advantageous in terms of RSS and there was no significant difference between groups in terms of aldrete scoring. Therefore, both groups have different advantages in terms of sedation, and we believe that both agents can be preferred safely.