Effects of the aetiologic and prognostic values in heart failure to life expectancy and the timing of mechanical circulatory support

İntroduction: The aim of this study, diagnosis, prognostic values investigate the relationship between prognosis in patients and mechanical circulatory support to determine the criteria for the early implantation in patients with heart failure. Methods: In this study, 40 (33 male, 7female) patients were included. Patients with dilated , ischemic and hypertrophic cardiomyopathy divided into groups. Optimal medical therapy were aplied to the patients at least 6 months before the study. New York Heart Association (NYHA) classes were identified, and Short Form (SF) 36 questionnaire was used to evaluate the quality of life. INTERMACS ®, degreement was defined. VO2 max and 6-minute walk test, blood sodium (Na), Pro-BNP, LVEF, right ventricular ejection fraction, right atrial filling pressures, right and left ventricular parameters were measured. Findings: The average age of patients were, 45.17±11.69. Dilated KMP, hypertrophic KMP, ischemic KMP 75%, 5%, 20% were respectively. NYHA class were class I 5%, class II 25%, class III and class IV 47.5% 22.5% respectively. Mean Intermacs levels were 4.90 ± 1.59 and 3.66 ± 1.22 and VO2 max values 13.52±6, 02, six-minute walk test, walking distances 280.55±131.94 meters, LVEF values were 23.10 ±6.73. In our study, evaluating the physical role in NYHA parameter values in group 2 was less than half compared to in group 1. ischemic KMP mortality was statistically significant (p <0.05). High SVDSÇ, low VO2 max values were associated with a poor prognosis (p <0.05). In multivariate analysis, right ventricular ejection fraction as independent variables were associated with death (p <0.05). Similarly, the six-minute walk test as an indicator of the independent predictors of mortality (p <0.01) . Conclusion: In our study, NYHA functional class worsened KF36 parameters were deteriorated. Because of the right ventricular ejection fraction 25% and in the walking test <200m, VO2 max values of 10 ml / kg / min of the results and the level of Intermacs to 3-4 in the bottom is seen as a poor prognosis, mechanical circulatory support is important to appear early decision. Having evaluated a large series of comorbid conditions associated with poor prognosis, In patients with dilated and ischemic KMP high mortality due to early decisions made in terms of MCS In our study, the high mortality associated with heart failure, mechanical circulatory support, suggest that selected patients may improve survival rates in the implementation. Key words: Heart failure, Life Expectancy, Cardiomyopathy