Cognitive states and depression levels of familial mediterranean fever patients subject to colchicine treatment

The study aimed to compare Familial Mediterranean Fever (FMF) patients' cognitive states and depression levels with healthy group who were not diagnosed as FMF. 30 FMF patients and 30 matched-healthy controls were included in the study as participants. To evaluate the demographic details, "Demographic Information Form" has given to the participants. "Rey- Osterrieth Complex Figure Test", "Raven Coloured Progressive Matrices" and "Stroop Test" were applied to measure cognitive functions. Depression levels were measured with "Beck Depression Inventory". Matched group design was used in the study. In order to examine the cognitive and emotional states of participants, mixed- design ANOVA and matched-pairs t-test were applied. As the results, FMF's drawing trial scores of Rey-Osterrieth Complex Figure Test were significantly higher than healthy/normal group. Furthermore, there were no significant differences between FMF and healthy/normal group in the light of "Raven Coloured Progressive Matrices", "Stroop Test" and "Beck Depression Inventory" scores. This study provides meaningful evidence to develop new researches about the FMF patients' cognitive states and depression levels.