Evaluation of hearing functions in patients with vitamin-Ddeficiency

Objective : Vitamin D is a both fat-soluble vitamin and hormone and hormone precursor sterols which can be synthesized endogenoulsy in suitable conditions. It is known to play an important role in calcium , phophorus metabolism and bone mineralization. Vitamin D deficiency have been associated with cardiovascular diseases , cancer, metabolic diseases, autoimmune diseases and many other diseases. Previous studies showing hearing loss in vitamin D deficiency are limited. Therefore, in this study, the effect of vitamin D deficiency on hearing loss will be investigated with more detailed tests. Expected to find out the effect of vitamin D in the inner ear hearing functions in this way. Individuals and Methods: As a result of the biochemical analyzes performed in the last 6 months, 30 individuals diagnosed with vitamin D deficiency and 30 individuals are diagnosed with vitamin D adequacy were included in the study. Inclusion criteria for participants are as follows ; those with a history of any audiological disease before the study are excluded, people with a history of open or closed head injury are excluded, those who start taking vitamin D supplements after diagnosis of vitamin D deficiency are excluded. In the control group, individuals with normal otoscopic examination, no history of head injury, and vitamin D levels above 26,02 ng / mL were included in the last 6 months. IBM Statistics SPSS 17 statistical program was used for the analysis of the data obtained. Results: The average age of individuals who is diagnosed with vitamin D deficiency is 32,30 ± 11,74 years. The average age of individuals who is diagnosed with vitamin D adequacy is 70 ± 14,47 years. The average level of vitamin D in individuals who is diagnosed with vitamin D deficiency is 12,28 ± 5,27 ng / mL and the average level of vitamin D in individuals who is diagnosed with vitamin D adequacy is 31,14 ± 3,79 ng/ mL . All individuals who is participated in this study has normal type tympanogram (Type A) . As conclusion of pure tone audiometry and TEOAE results, no statistically significant difference was found in any frequency tested for both right and left ear. Conclusion : Our findings do not show that vitamin D deficiency leads to the presence of auditory dysfunction that can be detected by pure tone audiometry and TEOAE tests. Key Words: Vitamin D deficiency, TEOAE, Multifrekans Tympanometry, Pure Tone Audiometry