Evaluation of clinical and laboratory parameters of hemophilia A and hemophilia B patients who apply to adult hematology polyclinic

Background: Hemophilia is a congenital hemorrhagic disorder due to X due to lack of factor VIII (hemophilia A) or factor IX (haemophilia B) from coagulation factors. Our aim in this study is to compare our data with the literature by establishing our own data by checking the clinical classification of hemophiliacs, the frequency of inhibitor development, kidney and liver function tests, and clinically, whether or not they have joint bleeding. Materials and Methods: This study included 64 male patients who were admitted to Dicle University Medical Faculty Research and Practice Hospital Internal Diseases Adult Hematology Clinic between December 2010 and April 2018 and who were diagnosed as hemophilia. The levels of inhibitors, whole blood, biochemistry, hormones, vitamins and coagulation parameters were examined in terms of the investigated studies of our patients. We investigated whether there was any joint hemorrhage or intracranial hemorrhage in the images. Results: A total of 64 patients were enrolled. The mean age of our patients was 26.4 ± 8.9 years (17-60 years). In our study, 85.9% (n = 55) of the patients were classified as hemophilia A and the remaining 14.1% (n = 9) as hemophilia B. In 85.9% of our patients (n = 55) the inhibitor level was negative. The rate of our patients who were regarded as having an inhibitor was 14.1% (n = 9). In 47.6% of the patients (n = 30), no joint hemorrhage was detected and in the remaining 52.4% (n = 33) hemorrhage was found in any joint. Conclusion: We think that we need more knowledge about our patients, increasing the number of responsibility and awareness projects for social life, and ultimately more literature on this subject, which affect the quality of life and aging joints with patients.