The relationship between autoanti̇bodi̇es and TSH i̇n hypothyroi̇di̇sm with RDW whi̇ch i̇s an i̇nflammati̇on marker

İNTRODUCTİON: Hashimoto's thyroiditis is most often autoimmune disease which being characterized lymphocytic infiltration of thyroid tissue. It is the most common cause of hypothyroidism in areas without iodine deficiency. Hashimoto's thyroiditis progresses with low-grade systemic inflammation. Chronic inflammation plays an important role in the progression of atherosclerosis. AIM: In this study serumRDW levels were detected in patients with Hashimoto's thyroiditis. We aimed to scan Increased cardiovascular events in patients, increased oxidative stress and and inflammation at no additional cost with using RDW. MATERIALS AND METHODS: A total of 904 persons, 462 patients with Hashimoto's thyroiditis and 442 age and sex matched control cases were included in the study. All data about patients were recorded. RESULTS: RDW was significantly increased in study group compared to control group (Hashimoto's thyroiditis =10.08 ± 4.48%, control = 8.95 ± 6.68%, p <0.05). Also MPV was increased in study group(p<0.05). hs-CRP showed a statistically significant positive correlation between the level of RDW. CONCLUSİON:RDW was increased in patients with Hashimoto's thyroiditis. KEY WORDS: RDW, Hashimoto's thyroiditis, MPV, inflammation, hs-CRP, thyroid autoantibodies