Investigation of the effect of phytic acid and its relationship with inhibin B, trace element and some biochemical markers in infertile men

Fertility is closely associated with the goodl desire of humans to live, reproduce, and prolong their existence. Objective: To measure the concentration of phytic acid and to study the effect of changes in its concentration on inhibin B and trace elements and some biochemical markers in infertile men, to assess spermatogenesis and semen parameters. There were high levels of phytic acid in men who had problems in the process of spermatogenesis, and thus its direct relationship to male infertility. That the presence of phytates in human food sources can form complexes in the metabolic stages of humans mainly insoluble with cations such as Ca, Mg and Zn, thus limiting or decreasing the bioavailability, these minerals are important in the formation of sperm. Men with high levels of phytic acid can experience changes in concenteration of inhibin B, LH, and FSH and thus directly affect the function of the male reproductive organs, which is evident in the third level of infertile men in our study. As for the low levels of inhibin B and LH, we found that it affects sperm motility and semen volume and thus limits sperm motility in males, which leads to incomplete fertilization. The study concluded that phytic acid can affect the metabolism of trace minerals, inhibin B hormone, LH and FSH, and thus lead to infertility or the development it or increase inability in treatment it. Because food is mainly based on plant products that contain phytate. There is a need for more studies on the effect of phytic acid on humans.