Medical SpecialtyOpen Access

The effects of platelet, PDW, MPV values on mortality in geriatric patients with hip fracture

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2022
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Advisor: Dr. Öğr. Üyesi Mahmut Yaman

Abstract (EN)

As in the world, there is an increase in the geriatric population in our country. With this increase, there is an increase in hip fracture cases. In hip fractures, which is a disease with high mortality and morbidity, the mortality rate increases up to 30% with increasing age. The most commonly performed surgeries among orthopedic emergencies are hip fracture surgeries in the elderly patient group. Especially in the elderly patient group with multiple comorbid factors, these surgeries are associated with high mortality. Thirty-day mortality rates in hip fractures are 5-13%, and one-year mortality is around 20-30%.In recent studies, it has been stated that parameters such as Platelet (PLT), Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW), known as Platelet Indices (PI), are biomarkers in platelet activation. These parameters, which are used to evaluate the disease levels of patients, can be measured quite easily and do not cause additional costs. It has been reported that platelets, which have important roles in hemostasis and thrombosis, contribute to the inflammatory process, microbial host defense, wound healing, angiogenesis and remodeling. It has been noted in the literature that the roles of platelet indices in the stages of thrombosis, angiogenesis, inflammation and immunity have also been investigated. Our study was carried out in Dicle University Medical Faculty Hospital Emergency Service. The data of patients with geriatric hip fractures admitted between 1 December 2019 and 1 December 2020 were analyzed. Our admission criteria consisted of both male and female patients over 65 years of age with hip fractures. The blood results and hip radiographs of the patients were evaluated. The patients whose clinical opinions were taken were analyzed as patients with indications for surgery and patients who did not undergo surgery after their clinical opinions. The patients were evaluated together with their blood results. Platelet, PDW and MPV values were examined in Whole Blood results of blood tests. Examined blood values (Platelet, PDW and MPV) of patients who died with hip fractures and those who survived were compared. The correlation of blood results of deceased patients with mortality was investigated. Keywords: Hip fracture, Geriatrics, Platelet, Mortality.

Author

Halime Özkan

How to Cite

Halime Özkan (Medical Specialty Thesis). The effects of platelet, PDW, MPV values on mortality in geriatric patients with hip fracture, 2022, Dicle University.

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