Irak'ta helikobakter pilori enfeksiyonu olan hastalarda immün tepki

In this study 40 patients were used in the experiment, 30 patients infected with H. Pyloriinfection and 10 for control, In this study the blood group, IFN-beta, and IL12 were collcted by Enzyme-linked Immuno Sorbent Assay (ELISA) technique, to define the H. pylori infection.The serum concentration of IL12 in patients infected with H.pylori was high level (162.314 ± 14.782) with a significant increase (p-value 0.0085), compared with healthy patients (control) (39.385 ± 6.819), and there was a significant increase (p-value 788) in serum concentration of IFN-beta in patients infected with H. pylori(168.360 ± 28.693) compared with healthy individuals (control) (50.640 ± 3.779). The Increase in IL12, IFN-beta in patients infected with h.pylori than the healthy patients showed us that the immunity system in infected patients resisted the pathogen, the aim of this study demonstrated the effect of the age risk factor on patients infected with helicobacter pylori and the effect of cytokines IFN-beta, IL12 in the immune response in patients infected with H. pylori, as a conclusion in this study older age consider as the main risk factor in patients infected with H. pyloriand cytokines (IL12,IFN-beta) level demonstrated immune response in patients with H. pylori.