The relationship between sleep quality with the clinical parameters, psychological state and the quality of life in patients with psoriatic arthritis

Introduction: Psoriatic arthritis (PsA) is an inflammatory disease associated with psoriasis. PsA is characterized by synovitis, dactylitis, enthesitis and spondylitis. Related to sleep quality, quality of life is being affected in patients with PsA. The aim of this study is to determine the influence of PsA on sleep quality and to reveal the relationship of sleep quality with the clinical parameters, quality of life and the psychological state. Material and method: Fourty one patients with PsA and 38 healthy volunteers were included into the study. Demographic and clinical characteristics including age, sex, disase duration, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) were recorded. Psoriatic Arthritis Quality of Life (PsAQoL), Psoriasis Area and Severity Index (PASI) scores were measured. Generalized pain assessed by visual analog scale (VAS). Anxiety ve depression scores were evaluated with Hospital Anxiety and Depression Scale (HADS) and sleep quality was evaluated with Pittsburgh Sleep Quality Index (PSQI) in both patient and control group. Result: Subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, daytime dysfunction and total PSQI were signifanctly higher in patients with PsA compared to control group. Total PSQI score was significiantly correlated with anxiety, generalized pain, PsAQoL, enthesitis, CRP and ESR levels (p<0,05). Conclusion: The sleep quality is disturbed in patients with PsA. Sleep disturbance is especially associated with generalized pain, anxiety, enthesitis, ESR and CRP levels in patients with PsA. Keywords: Psoriatic arthritis, sleep quality, psychological status, generalized pain, enthesitis.