Evaluation of the conduction system of the heart in patients with atrial septal defect WHO underwent transcatheter closure

Aim. In this study, it was aimed to evaluate the conduction system of the heart in patients with ASD, to examine clinical, electrocardiographic and laboratory findings before and after closure, and to determine the factors that may affect prognosis and survival. Method. The files of patients diagnosed with ASD who were followed up between February 2016 and June 2020 at Van Yüzüncü Yıl University (YYÜ) Faculty of Medicine, Division of Pediatric Cardiology and who underwent transcatheter closure were retrospectively analyzed. The results of ASD cases were compared with the control group, and cardiac parameters before and after closure in ASD cases were compared. Results. 42.5% of the cases treated with the diagnosis of ASD and 52.5% of the control group were male. The mean age of ASD cases was 8.8 ± 4.5, and the mean age of the control group was 9.6 ± 3.9. There was no significant difference between the ASD cases and the control group in terms of gender and age (p> 0.05). Compared to the control group, the systolic blood pressure of ASD cases was statistically significantly lower (p = 0.025). There was no statistically significant difference between the ASD patients and the control group in terms of body weight, peak heart rate and diastolic blood pressure values (p> 0.05). When compared with the control group, the calcium level of ASD cases was statistically significantly higher (p <0.001). There was no statistically significant difference between ASD cases and the control group in terms of other laboratory values (p> 0.05). When compared with the ECG parameters of the control group, Pmin and QTcmin times before transcatheter closure were statistically significantly shorter and Pdis, QTdis, and QTcdis times were statistically significantly longer in ASD cases (p <0.05). When compared with the ECG parameters of the control group, Pmax, Pmin, QTcmin times were statistically significantly shorter, and the times of QTmax, QTdis and QTcdis were statistically significantly longer after transcatheter closure in ASD cases (p <0.05). Compared to the ECG parameters before transcatheter closure in ASD cases, Pmax and Pdis times were statistically significantly shorter, and the QTmin duration was statistically significantly longer after transcatheter closure (p <0.05). Conclusion. In our study, it was found that while Pmax and Pdis durations were shortened after closure, QTmin duration was prolonged in ASD cases compared to before transcatheter closure. Compared to the control group, Pmin and QTc min times were shorter, while Pdis, QTdis and QTcdis times were longer before ASD closure. There is a need for prospective electrophysiological studies, including 24-hour ECG and / or longer ECG recordings, with the participation of more patients, showing the effectiveness of transcatheter closure therapy on atrial and ventricular arrhythmias in ASD cases.